MTHFR - Again

 

I discovered this issue around 2013ish.  I’ve been researching it ever since.  This is one of the best articles I have ever seen about the problem.

https://open.substack.com/pub/curingcoviddiseases/p/its-all-about-methylation-everything?r=1736yu&utm_medium=ios&utm_campaign=post

Here is my brief summary of this article:

B9

Is methylated in the body by the MTHFR enzyme, produced by the MTHFR gene…

Into

5-MTHF

To make the MTHFR enzyme, you need methyl donors from:

Betaine

Choline and/or

Methionine

(From food)

Food alone isn’t sufficient. Your body must be able to make the MTHFR enzyme.  Supplements that help this process along are:

SAMe

5-MTHF (a form of B9)

Methylcobalamin (a form of B12)

These 3 supplements don’t work the same on everybody.

B12 is CRITICAL to the methylation process

There are 4 forms of B12 - each work differently.

B12 as Methylcobalamin is the best choice.

The COMT gene also affects the methylation process

There are 2 forms:

SLOW COMT

Or

FAST COMT

Each requires a different supplementation protocol.

People with methylation issues often have histamine reactions

And to complicate things:

DNA Methylation turns genes off or on

A gene can either be turned on, expressing itself

Or

Turned off, not expressing itself - it causes no problem

If there are sufficient methyl donors in the body to attach to the DNA, the gene will turn OFF.  And vice versa.

So when a medical “professional” tells you, lots of people test positive for a 677 or 1298 MTHFR gene defect, and they’re just fine, because they have no issue.  So it’s not a problem.  And the actual situation is that the gene is just turned off because this particular body has sufficient methyl donors available.

The article then provides great advice about 

WHAT SHOULD I DO NOW?

Specific action steps to regain your health.